INS and type 2 diabetes mellitus: Although both the OB-RYGB and T2D-RYGB groups demonstrated a much greater early postprandial increase in insulin secretion than the OB-LAGB and T2D-LCD groups, the ISR in relation to plasma glucose was not different between the participants who had RYGB and those who had lost the same amount of weight after LAGB or a LCD alone.