INS and type 2 diabetes mellitus: However, plasma glucose concentration AUC0–200 decreased after weight loss in both the T2D-RYGB group and the T2D-LCD group, without a difference between the 2 groups, whereas weight loss did not affect plasma insulin concentration AUC0–200 in either the T2D-RYGB or the T2D-LCD groups (Table 2 and Figure 2F).