In the colon, we observed decreased tumor incidence (Figure 3B) and volume (Figure 3C) in ApcΔIE/+ Selenop–/– mice as compared with ApcΔIE/+ Selenop+/+ or Selenop+/– mice, despite similar survival rates (Figure 3D), numbers (Figure 3E), and dysplasia severity (Figure 3, F and G). Here, SELENOP is linked to neoplasm.