Similarly, in a single-nucleus RNA-Seq (snRNA-Seq) data set generated from patients with familial adenomatous polyposis (FAP) and from non-FAP patients (29) (Supplemental Figure 5B), SELENOP expression was greater in adenocarcinomas than in polyps or unaffected stem cells (Supplemental Figure 5C). Here, SELENOP is linked to Familial adenomatous polyposis.