LRIG1 and neoplasm: Tamoxifen-induced Lrig1-CreERT2/+ Apcfl/+ Selenop+/+, Selenop+/–, and Selenop–/– cohorts (hereafter referred to as ApcΔIE/+ Selenop+/+, Selenop+/–, and Selenop–/– mice) were monitored for tumor formation via colonoscopy and euthanized after 100 days (Figure 3A).