Similarly, in the small intestine, we observed decreased tumor areas (Supplemental Figure 6A) in ApcΔIE/+ Selenop–/– mice as compared with ApcΔIE/+ Selenop+/+ or Selenop+/– mice, despite similar incidence rates (Supplemental Figure 6B), numbers (Supplemental Figure 6C), and dysplasia severity (Supplemental Figure 6, D and E). Here, SELENOP is linked to neoplasm.