Previous studies have found that AT2 cells positive for Forkhead box M1 (FoxM1) and Stem cell antigen 1 (Sca1) function as stem cells after infection with Pseudomonas aeruginosa (PA), and differentiate to AT1s to play a repair role under the stimulation of Wnt signaling [27, 28]. The gene discussed is FOXM1; the disease is infection.