TP53 and cervical squamous intraepithelial neoplasia: Loss of p53 function and TP53 mutation have been defined as the earliest driver events permitting the development of diverse chromosomal instability (CIN) phenotypes that are apparent in pre-invasive lesions in the fallopian tubal epithelium (Ahmed et al., 2010; Labidi-Galy et al., 2017).