F‐LP formed stable lipoplexes with the DNA methyltransferase 1 (DNMT1) gene (gDNMT1), namely, F‐LP/gDNMT1, which resulted in successful tumor growth inhibition of both paclitaxel‐sensitive and paclitaxel‐resistant ovarian cancers as well as downregulated DNMT1 in vivo (ref). The gene discussed is DNMT1; the disease is ovarian carcinoma.