As shown in Table 1, hemoglobin (HBA1/HBA2), lactoferrin (LTF), complement (C3), defensin (DEFA3), S100 families, and cathelicidin antimicrobial peptides (CAMP/LL-37) were among the top 10 molecules with the greatest increase in expression in SLE B cells. The gene discussed is C3; the disease is systemic lupus erythematosus.