PRDX3 protein, a hydrogen peroxide scavenger produced by mitochondria, was significantly overexpressed in LRRK2 PD vs. NMC (Fold-change = 580, p-value = 4.05E-14) and in LRRK2 PD vs. iPD (Fold-change = 665, p-value = 5.07E-22), respectively (see Fig. 3a, b, see Supplementary Data 4 for table format). The gene discussed is PRDX3; the disease is Parkinson disease.