CHKA and neoplasm: Following ST analysis revealed that FASN, SCD, FADS and ELOVL genes which catalyze the synthesis, elongation, and desaturation of FA; CHKA and ETNK1 genes which regulate phospholipid synthesis; PLD and LYPLA2 genes which control lipid metabolism; CPT1A and CRAT genes which catalyze the β-oxidation of FA all showed up-regulated expressions in tumor tissues (Fig. 4f, g, and Supplementary Fig. 43).