GPR84 and acute myeloid leukemia: GPR84 is the recognizer of medium-chain fatty acids (C9–C14) including capric acid (C10), undecanoic acid (C11), and lauric acid (C12).113 The levels of GPR84 expression are significantly upregulated in human and mouse acute myeloid leukemia (AML) leukemic stem cells (LSCs) compared to normal hematopoietic stem cells (HSCs).