We used WS5R “rescued” hiPSC line wherein WFS1 cDNA under a doxycycline (Dox) inducible promoter was introduced via CRISPR-Cas9-mediated knockin at the AAVS1 locus in WS patient-derived WS5 hiPSC line (Pourtoy-Brasselet et al., 2021). This evidence concerns the gene PPP1R12C and Werner syndrome.