Correspondingly, docetaxel therapy enhanced intratumor-infiltrating T cells in a PCa xenograft mouse model and promoted the expression of programmed cell death-1 (PD1) and programmed cell death-ligand 1 (PD-L1), potentiating the anti-PD1 blockade therapeutic effect in PCa xenograft mice. This evidence concerns the gene CD274 and posterior cortical atrophy.