There are also other tests, such as those of soluble intercellular adhesion molecule-1, interleukin-6, matrix metalloproteinase-9, tissue inhibitor of metalloproteinases-1, angiopoietin-2, and insulin-like growth factor binding protein-2, which are not used much in routine examinations but can be used to predict chorioamnionitis [5,6]. The gene discussed is IGFBP2; the disease is chorioamnionitis.