TLR2 and gastric cancer: With regards to validating our pilot study findings that identified TLR2 and TNF genetic and colorectal and gastric cancer type non-genetic predictors of overall GI toxicity [11], a combined model in the current study only improved the % AUC of ROC curves from the genetic predictors model by 6% and observed different genetic (TGFB1) and non-genetic predictors.