To further investigate the functional role of FBLN2 in HCC, the HCC cell lines Bel-7402, HCCLM3, SNU449, and SNU398 were transduced with lentiviral expression vectors and stable overexpression or knockdown of FBLN2 was confirmed at the protein level (shown in Figure 2A and Supplementary Figure 1). Here, FBLN2 is linked to hepatocellular carcinoma.