CD4 and neoplasm: Specifically, CIBERSORT demonstrated that the ADAR1 high expression group had a higher proportion of CD8+ T cells, activated CD4+ memory T cells, resting natural killer cells, M0 macrophages, and M1 macrophages in tumor tissues, whereas there were more monocytes, resting dendritic cells, M2 macrophages and resting mast cells infiltrating in the low expression group (Figure 4).