Conventional DCs (CD45+CD11c+MHC‐II+), especially CLEC9A+ type 1 conventional DCs (cDC1) subset, play a critical role in tumor antigens trafficking and antitumor T cell priming, which is closely related to the efficacy of tumor immunotherapies.[22] The treatment with FK‐13 promoted the bone marrow cells differentiation into conventional DCs, CLEC9A+ cDC1 subpopulation and enhanced the expression levels of costimulatory molecules on DCs, including CD40, CD80, CD86 (Figure 1D–H), indicating the activation of DCs. This evidence concerns the gene CD80 and neoplasm.