In addition, several studies have constructed ceRNA networks closely related to the pathogenesis of CRC through bioinformatics methods [18, 19].The MIR4435-2HG- and ELFN1-AS1-associated ceRNA subnetworks affected and regulated the expression of the seven target genes and were found to be related to prognosis and tumor-infiltrating immune cell types [18]. This evidence concerns the gene ELFN1 and colorectal carcinoma.