They are ‘host-coronavirus interaction’, ‘organism’, ‘AA variant in SARS-CoV-2 S protein’, ‘device’, ‘COVID-19 diagnostic testing device’, ‘amino acid’, and ‘alpha-amino acid.’ However, increasing b makes the two nodes ‘COVID-19 subunit vaccine’ with a weight 54 and ‘COVID-19 RNA vaccine’ with a weight 38, shown at the bottom in Fig. 6, considered as small nodes and they are aggregated into their parent node ‘COVID-19 vaccine’ in Fig. 8. The gene discussed is PROS1; the disease is COVID-19.