Through the reprogramming of glucose metabolism by regulating miR-3189-inhibited GLUT3 expression, their results showed the critical function of histone deacetylase 2 in the development of glioblastoma tumors and provided a possible novel therapeutic approach for the treatment of glioblastoma multiforme (GBM) [23]. The gene discussed is HDAC2; the disease is glioblastoma.