BARX2 and lung adenocarcinoma: Although BARX2 expression is upregulated in various types of tumours, such as lung adenocarcinoma, ovarian serous adenocarcinoma and nasopharyngeal cancers25,32,33, the current study shows that BARX2 is also expressed downregulated in different types of tumours such as breast, gastric and colon cancers24,29,31, suggesting that BARX2 expression is tissue specific.