In our study, Pcdhgb2 KO mice showed mild renal and cardiovascular phenotypes substantiated by the lower albumin and elevated amylase blood levels, anemia, increased T cells, severe hydronephrosis in one mutant mouse and the reduction of LV cavity due to a thickening (e.g., hypertrophy) of the heart wall. Here, PCDHGB2 is linked to anemia (phenotype).