In pigs, PGE-530742 (renamed to PG-116800, inhibiting MMP-2, -3, -8, -9, -13, and -14, sparing MMP-1 and -7) as well as PD166793 (inhibiting MMP-2, -3 and -13 sparing MMP-1, -7 and -9) attenuated LV remodelling after MI [89, 139]. This evidence concerns the gene MMP2 and myocardial infarction.