The qRT-PCR data revealed that the expression level of TNF-α, Il-1β, TGF-β, and Bcl2 was significantly upregulated as well as significantly down-regulated of Bax, and Bec1 in the HCC group in comparison with the untreated control group, while the administration of SOR and/or CLT significantly downregulated the expression level of TNF-α, Il-1β, TGF-β, and Bcl2, and significantly upregulated the expression of Bax, and Bec1 compared to the untreated HCC group. The gene discussed is IL1B; the disease is hepatocellular carcinoma.