CDK2 and neoplasm: The interaction network showed that FOXM1 was closely correlated with those proteins who are involved in the cell cycle, such as cyclin-dependent kinase 1 (CDK1), CDK2, Cyclin B1 (CCNB1), as well as CCNB2, indicating FOXM1 may act as an important regulator of the tumor cell cycle (Figure 3(c)).