STAT3 and neoplasm: Additionally, treating with Pc-STAT3 and miR-125-5p could increase the cell viability of U-20S/DX580 and Sao-2/DX580 compared with that using miR-125-5p mimic and pc-NC, which means that the effect of miR-125-5p to inhibit tumor cell drug resistance is removed by STAT3 (Figure 6(a)).