Similarly, genes shared between endometriosis, uterine fibroids, ovarian cancer, migraine and depression (RHOA, FOXP1, ESR1, WNT4, GREB1, FSHB), and endometriosis, migraine and asthma (IGF1, SMAD3, MFHAS1), were enriched in hormone receptor signalling and inflammation pathways, respectively (Adewuyi et al., 2020, 2021, 2022; Mortlock et al., 2022). Here, ESR1 is linked to major depressive disorder.