Based on their known functions, all three genes at the 1p36.12 locus have the potential to contribute to the formation and progression of lesions characteristic of endometriosis, fibroids and cancer whilst WNT4, LINC0039, MLLT10, and SKAP1 have known roles in respiratory physiology and/or immune regulation, which are also important factors in asthma and cancer. This evidence concerns the gene WNT4 and asthma.