FSH subunit beta (FSHB), encoding the beta subunit of a pituitary glycoprotein that indices gamete production, was associated with endometriosis, uterine fibroids and migraine (Gallagher et al., 2019; Adewuyi et al., 2020), and previous studies also link it to reproductive lifespan, menstrual cycle characteristics, FSH concentrations, and PCOS (McGrath et al., 2021). This evidence concerns the gene FSHB and migraine disorder.