PPFIA1 and neoplasm: Our results showed that high PPFIA1 expression was positively related to tumor invasion depth (P = 0.019), lymph node metastasis (P = 0.013), and TNM stage (P = 0.012), but no correlations were found between PPFIA1 expression and gender, age, smoking use, alcohol use, tumor location, histological grade or adjuvant therapy (P > 0.05) (Table 1).