To determine the exact role of HSP70 in GCRV infection and which stage of viral infection is influenced by HSP70, we employed HSP70-specific inhibitor quercetin (Que) (25) and VER-155008 (VER) (26) to incubate CIK cells, and a cell viability assay showed that all the drugs we used under our experimental conditions had a negligible cytotoxic effect on the cells (Fig. S3A). Here, HSPA1A is linked to viral infectious disease.