TINCR and colorectal cancer: TINCR can interact with copious mRNAs and proteins to manipulate mRNA differentiation.30,31 Previous studies implied that TINCR is closely related to the proliferation and apoptosis of cells in various tumors, including breast cancer, gastric cancer, and hepatocellular carcinoma.30,32,33 Zhang et al34 and Ren et al35 proved that overexpressed TINCR could repress the proliferation of colorectal cancer cells and facilitate apoptosis.