EZH2 and inflammatory bowel disease: As gene expression networks of CD4+ T cells extracted from intestines of IBD patients indicated disrupted EZH2 networks and differential expression of proinflammatory genes typical of Th1/Th17 effector T cells, one can claim that deregulation of EZH2-enforced T-cell gene networks leads and maintains intestinal inflammation in both murine models and human IBD.