To verify whether TQHXD protected the gut from inflammation via CX3CR1, we subjected CX3CR1GFP/+ and CX3CR1GFP/GFP reporter mice, in which CX3CR1 is replaced with GFP on macrophages in one and two alleles, respectively, to a TBI‐induced colitis model. The gene discussed is CX3CR1; the disease is colitis.