APOA1 and deep vein thrombosis: In the MR analyses, we found that there was no causal relationship between APOA1 (exposure) and DVT (outcome) using the various MR analysis methods (IVW (random effects): Beta = − 3e−4, Pbeta = 0.870; weighted median: Beta = − 0.001, Pbeta = 0.480; weighted mode: Beta = − 0.001, Pbeta = 0.447; simple mode: Beta = − 4e−4, Pbeta = 0.847; MR‒Egger: Beta = − 0.006, Pbeta = 0.291) (Table 1, Fig. 1).