HNRNPC and breast cancer: In agreement with a potential role for HNRNPC involvement in a translational deregulation programme in metastatic breast cancer, HNRNPC was modestly but significantly downregulated in highly metastatic cells, both at the mRNA (log fold change −0.5, P = 0.05, determined by RNA-seq) and protein level (log fold change of −0.24, P = 0.04, determined by mass spectrometry (MS)14).