EYA4 and cancer: The expression of EYA4 was significantly upregulated in 6 types of cancers (ESCA, PAAD, GBM, OV, SKCM, and UCS), and downregulated in 13 types of cancers (LUAD, ACC, BLCA, BRCA, KIRC, HNSC, KIRP, CESC, COAD, DLBC, LUSC, KICH, LAML, LGG, LIHC, READ, THCA, PRAD, THYM, and UCEC) (Fig. 1D).