To further analyze the immune infiltration in HCC, we performed ssGSEA and found that T helper 2 (Th2) cells, T helper cells, and plasmacytoid dendritic cells (pDC) were higher infiltration in HCC in all four datasets, gamma delta T cells (Tgd), Neutrophils, DC, cytotoxic cells, and CD8 T cells were lower infiltration in HCC (Fig. 6C). This evidence concerns the gene CD8A and hepatocellular carcinoma.