Several multicenter clinical research have found that single nucleotide mutations (SNPs) in m6A-related enzymes METTL3 [13], METTL14 [14], WTAP [15], YTHDF1 [16], YTHDC1 [17], and YTHDF2 [18] are associated with NB appearance and progression. This evidence concerns the gene METTL3 and neuroblastoma.