Moreover, a recent study also implicated Rab10 in AD-associated tau pathology, showing that LRRK2-mediated phosphorylation of Rab10 at Threonine 73 (pRab10-T73) leads to colocalization of pRab10-T73 with pTau (Yan et al., 2018). This evidence concerns the gene RAB10 and Alzheimer disease.