KMT2A and acute myeloid leukemia: In a mouse model of MLL-AF9-driven leukemogenesis, KAT8 gene deletion was associatedwith a decrease in acute myeloid leukemia (AML) cell proliferation.16KAT8 is also overexpressedin endometrial carcinoma tissues, with its expression being associatedwith metastasis and shorter patient survival.