Moreover, through the phosphoinositide 3‐kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) pathway, deoxyshikonin induces apoptosis and cell arrest in the G0/G1 cell cycle in human colorectal cancer HT29 cells and suppresses tumour growth in xenograft mice transplanted with human colorectal cancer DLD‐1 cells.22 This evidence concerns the gene AKT1 and colorectal cancer.