Among the 406 participants (137 Aβ-positive CU, 144 Aβ-positive MCI, and 41 AD dementia) with longitudinal [18F]flortaucipir tau PET, the mean (SD) age was 77.18 (7.74) years, and 41 were female (48.32%) (eTable 14 in Supplement 1). The gene discussed is MAPT; the disease is Alzheimer disease.