Meanwhile, according to the above studies, IFNG was significantly positively correlated with the PD-1/PD-L1 pathway and immunotherapy response in breast cancer, so we focused on IFNG. In the TCGA dataset, the samples with high expression of IFNG had a better prognosis (P < 0.01) (Fig. 8B). The gene discussed is PDCD1; the disease is breast cancer.