Phospho-tau (AT8) specific staining was comparable to that of GT38 with seeding doses strongly correlated in AD cases to %AO AT8 and tau for both grey and white matter (r = 0.71, p = 0.02 and r = 0.62, p = 0.04 respectively) (Fig. 3). The gene discussed is MAPT; the disease is Alzheimer disease.