NCK-associated protein 1 (NCKAP1) and guanine nucleotide exchange factor Vav 3 (VAV3), MYO10, and Wiskott-Aldrich syndrome protein (WASp), known intracellular signaling-regulated factors related to the actin-polymerization process in phagocytosis [42], were significantly decreased in ALS(R)-iMGs. This evidence concerns the gene VAV3 and amyotrophic lateral sclerosis.