In addition to numerous studies expounding the mechanisms of anti‐apoptotic function of XIAP, a few studies have revealed that XIAP overexpression promotes colon cancer cell invasion via inhibiting Rho‐GDIα SUMOylation43 and facilitates bladder cancer invasion and lung metastasis via enhancing nucleolin‐mediated Rho‐GDIβ mRNA stability.4 The gene discussed is XIAP; the disease is malignant colon neoplasm.