To investigate whether Apobec3A SUMOylation may be increased during infection, HepaRG-His-SUMO2, stably expressing 6×His-SUMO2, and control HepaRG-His/HA cells were transfected with pLenti6.3-Apobec3A-V5 and were superinfected with HAdV wt. This evidence concerns the gene APOBEC3A and infection.