Interestingly, exercise intolerance, muscle fatigue, and histopathology are also observed in the rare KATP channelopathy, Cantú Syndrome, which arises from gain‐of‐function mutations in either ABCC9 (SUR2) or KCNJ8 (Kir6.1; Grange et al, 2019; Scala et al, 2020; Scala et al, 2021). Here, ABCC9 is linked to hypertrichotic osteochondrodysplasia Cantu type.