Strikingly, in human hearts, the miR–129-5p/Ddr2 ratio was inversely correlated with LV interstitial fibrosis and expression of ASPN and SOX9 in CF as well as with a trend toward inverse correlation with myocardial calcification in fibrotic areas (Figure 2, B–E). The gene discussed is DDR2; the disease is cystic fibrosis.