This study highlights the potential role of BRIP1 in pan-cancer as a predictor for diagnosis, prognosis, and treatment response through in-depth analyses of differential expression, relationships between BRIP1 and different prognostic parameters, gene functions, regulatory pathways, TME, TIICs, immune-related genes, and TMB-MSI as well as anticarcinogen. Here, BRIP1 is linked to cancer.