Curcumin (10 μmol L-1) inhibits the activation of the TXNIP/NLRP3 pathway by up-regulating AMPK activity in human neuroblastoma SH-SY5Y cells of human neuroblastoma and reducing ROS produced by endoplasmic reticulum stress (Li et al., 2015). This evidence concerns the gene NLRP3 and neuroblastoma.