EGFR and hepatocellular carcinoma: Huang M et al. (Huang et al., 2022b) performed unbiased proteomic screening of parental and LVN-induced resistant HCC cells (PLC/PRF/5, Hep3B, and Huh7) and discovered two important N7-methylguanosine (m7G) tRNA methyltransferase complex components, which influenced the function related with EGFR translation.